Transplant & Veno-Occlusive Disease (VOD)

Joseph Antin, MD

Many may be familiar with graft versus host disease (GVHD) however, veno-occlusive disease (VOD), otherwise known as sinusoidal obstruction syndrome (SOS), is also one of the most frequently encountered complications after stem cell transplantation. Listen in as Alicia and Lizette from The Leukemia & Lymphoma Society (LLS) speak with Dr. Joseph Antin, Chief of the Stem Cell Transplant Program of the Department of Medical Oncology at Dana Farber Cancer Institute and Brigham and Women’s Hospital in Boston, Massachusetts. On this episode they will discuss the difference between a bone marrow and stem cell transplant, treating VOD, autologous and allogeneic transplants, how doctors choose the cell source collected from the blood or the marrow that is best for the patient, VOD as it presents in pediatric and adult patients and interesting findings about herbal tea induced hepatic veno-occlusive disease.

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Support for this program provided by Jazz Pharmaceuticals.


  1. Thank you very much for a very interesting and informative discussion of VOD and stem cell transplantion in general. My 71-year-old husband is considering stem cell transplantation for CMML, so this was very helpful for him to hear.

    Wendy and Jerry Paley

    1. Excellent information. My husband considering bone marrow transplant. He is 71 years old and diagnosed with ALL.

      Barb Brotschul

      1. Thank you for listening to The Bloodline with LLS! To order free publications about transplant and/or ALL, or to speak with one of our Information Specialists, please call (800) 955-4572, Monday – Friday, 9am – 9pm ET.

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